TY  - BOOK
AU  - Dion-Côté, Anne-Marie
AU  - Barbash, Daniel A.
AU  - Clark, Andrew G.
AU  - Lower, Sarah E.
AB  - Repetitive DNA is ubiquitous in eukaryotic genomes, and, in many species, comprises the bulk of the genome. Repeats include transposable elements that can self-mobilize and disperse around the genome, and tandemly-repeated satellite DNAs that increase in copy number due to replication slippage and unequal crossing over. Despite their abundance, repetitive DNA is often ignored in genomic studies due to technical challenges in their identification, assembly, and quantification. New technologies and methods are now providing the unprecedented power to analyze repetitive DNAs across diverse taxa. Repetitive DNA is of particular interest because it can represent distinct modes of genome evolution. Some repetitive DNA forms essential genome structures, such as telomeres and centromeres, which are required for proper chromosome maintenance and segregation, whereas others form piRNA clusters that regulate transposable elements; thus, these elements are expected to evolve under purifying selection. In contrast, other repeats evolve selfishly and produce genetic conflicts with their host species that drive adaptive evolution of host defense systems. However, the majority of repeats likely accumulate in eukaryotes in the absence of selection due to mechanisms of transposition and unequal crossing over. Even these neutral repeats may indirectly influence genome evolution as they reach high abundance. In this Special Issue, the contributing authors explore these questions from a range of perspectives.
DO  - 10.3390/books978-3-03928-367-5
ID  - OAPEN ID: 44771
KW  - transgene
KW  - zebra finch
KW  - transcription
KW  - endogenous retrovirus
KW  - transposable element
KW  - centromere drive
KW  - arthropods
KW  - PSR (Paternal sex ratio)
KW  - Alu
KW  - gene evolution
KW  - nuclear rDNA
KW  - epigenetics
KW  - heterochromatin
KW  - alpha satellite
KW  - Su(Hw)
KW  - repeated elements
KW  - karyotype
KW  - piRNA cluster
KW  - gene duplication
KW  - super-Mendelian
KW  - estrildidae
KW  - genomic conflict
KW  - GC-content
KW  - segregation
KW  - CENP-A
KW  - drift
KW  - germline
KW  - hobo
KW  - I element
KW  - repetitive DNA
KW  - transposons
KW  - human satellites
KW  - retrotransposons
KW  - genome assembly
KW  - LTR retrotransposons
KW  - satellite DNA
KW  - structural variation
KW  - selection
KW  - host genome
KW  - Uraeginthus cyanocephalus
KW  - LINE-1
KW  - B chromosomes
KW  - ERV
KW  - arms race
KW  - sequence variation
KW  - secondary structure
KW  - HeT-A and TART telomeric retrotransposons
KW  - database
KW  - genetic conflict
KW  - coevolution
KW  - ncRNAs (non coding RNAs)
KW  - repeat
KW  - centromeric transcription
KW  - nucleolus
KW  - satellite
KW  - insulator
KW  - Rhino
KW  - population genetics
KW  - centromere
KW  - genome annotation
KW  - horizontal transfer
KW  - rRNA
KW  - genome elimination
KW  - genome evolution
KW  - evolution
KW  - chromosome evolution
KW  - genome size
KW  - genome
KW  - drosophila
KW  - transposable elements
KW  - selfish elements
L1  - https://mdpi.com/books/pdfview/book/2048
LA  - English
LK  - https://directory.doabooks.org/handle/20.500.12854/58231
PB  - MDPI - Multidisciplinary Digital Publishing Institute
PY  - 2020
SN  - 9783039283675
SN  - 9783039283668
TI  - Repetitive DNA Sequencesnull
ER  - 
