TY  - BOOK
AU  - Downie, Laura
AU  - Lawrenson, John
AB  - Blindness and visual impairment impact significantly on an individual’s physical and mental well-being. Loss of vision is a global health problem, with approximately 250 million of the world’s population currently living with vision loss, of which 36 million are classified as blind. Visual impairment is more frequent in the elderly, with cataract and age-related macular degeneration (AMD) accounting for over 50% of cases globally. Oxidative stress has been strongly implicated in the pathogenesis of both conditions, and consequently the role of nutritional factors, in particular carotenoids and micronutrient antioxidants, have been investigated as possible preventative or therapeutic strategies. Dry eye syndrome (DES) is one of the most common ophthalmic conditions in the world. DES occurs where the eye does not produce enough tears and/or the tears evaporate too quicklyleading to discomfort and varying degrees of visual disturbance. There has recently been a great deal of interest in the potential for oral or topical supplementation with essential fatty acids (EFAs), specifically omega-3 and omega-6 fatty acids, as an adjunct to conventional treatments for DES. The objective of this Special Issue on ‘Nutrition and Eye Health’ is to publish papers describing the role of nutrition in maintaining eye health and the use of nutritional interventions to prevent or treat ocular disease. A particular (but not exclusive) emphasis will be on papers (reviews and/or clinical or experimental studies) relating to cataract, AMD and DES.
DO  - 10.3390/books978-3-03921-991-9
ID  - OAPEN ID: 43611
KW  - polyphenols
KW  - n/a
KW  - crocin
KW  - chyrsin
KW  - glaucoma
KW  - dietary assessment
KW  - photoreceptor degeneration
KW  - dry eye
KW  - RR-zeaxanthin
KW  - nutritional supplements
KW  - drug discovery
KW  - corneal neovascularization (CNV)
KW  - AMD
KW  - dietary antioxidants
KW  - micronutrients
KW  - age-related macular degeneration
KW  - preclinical models
KW  - lenses
KW  - microvascular lesions
KW  - cyclooxigenase-2 (COX-2)
KW  - angiogenesis
KW  - fish oil
KW  - macrophage
KW  - anti-oxidant
KW  - vascular endothelial growth factor (VEGF)
KW  - rosmarinic acid
KW  - visual cycle
KW  - diabetic retinopathy
KW  - lutein
KW  - gut-retina axis
KW  - light damage
KW  - crocetin
KW  - supplements
KW  - clinical practice guidelines
KW  - nutrition
KW  - light
KW  - eye disease
KW  - dietary habits
KW  - flavonoids
KW  - phytoconstituents
KW  - saffron
KW  - carotenoids
KW  - fatty acid
KW  - electroretinography
KW  - lens
KW  - advanced glycation end products
KW  - interleukin-1? (IL-1?)
KW  - mesozeaxanthin (RS zeaxanthin)
KW  - endoplasmic reticulum stress
KW  - omega-3 polyunsaturated fatty acids
KW  - clinical survey
KW  - corneal chemical burn
KW  - reduced glutathione
KW  - omega-3
KW  - AGREE II
KW  - retina
KW  - inflammation
KW  - anti-inflammatory
KW  - retinal pigment epithelium
KW  - diet
KW  - Lactobacillus paracasei KW3110
KW  - Crocus Sativus L.
KW  - saponins
KW  - cataract
KW  - CODS
KW  - neoangiogenesis
KW  - estrogen-deficient rats
KW  - food frequency questionnaire
KW  - gut microbiota
KW  - antioxidant supplements
KW  - sinapic acid
KW  - personalised medicine
KW  - systematic reviews
KW  - nuclear factor-kappaB (NF-?B)
KW  - diabetes
KW  - Cucurbita argyrosperma
KW  - oxidative stress
KW  - endoplasmic reticulum
L1  - https://www.mdpi.com/books/pdfview/book/1918
LA  - English
LK  - https://directory.doabooks.org/handle/20.500.12854/54960
PB  - MDPI - Multidisciplinary Digital Publishing Institute
PY  - 2020
SN  - 9783039219919
SN  - 9783039219902
TI  - Nutrition and Eye Healthnull
ER  - 
