TY  - BOOK
AU  - Pinar Erkekoglu
AB  - Oncogenes are mutated and/or overexpressed at high levels in tumor cells. Tumors of the lung, breast, pancreas, and colon may display specific oncogenetic features. These tumors have been largely associated with exposure to environmental carcinogens and a variety of biological agents, including viruses. These carcinogens can induce specific genetic and epigenetic alterations in these tissues, leading to aberrant functioning of oncogenes and tumor suppressor genes. On the microRNAs (miRNAs) there are significant modifiers of both transcription and translation of oncogenes in carcinogenesis. In the last 50 years, several oncogenes and microRNAs related to these oncogenes have been identified in different types of human cancers. It is now clear that high expression of oncogenes, DNA damage response, and regulation of the cell cycle are related to the circadian clock. This book will mainly focus on the expressions of different oncogenes in breast, colon, and lung cancers. Moreover, readers will gain qualified scientific knowledge of the alterations in miRNAs in different types of cancers and the effects of the circadian clock on the expression of oncogenes in carcinogenesis.
DO  - 10.5772/intechopen.74727
ID  - OAPEN ID: 37790
KW  - Life Sciences
KW  - Genetics and Molecular Biology
KW  - Oncology
KW  - Biochemistry
KW  - Cancer Biology
L1  - https://www.intechopen.com/books/oncogenes-and-carcinogenesis
LA  - English
LK  - https://directory.doabooks.org/handle/20.500.12854/55222
PB  - IntechOpen
PY  - 2019
SN  - 9781789851724
SN  - 9781789851717
TI  - Oncogenes and Carcinogenesisnull
ER  - 
