TY - BOOK AU - Holban, Alina Maria AU - Grumezescu, Alexandru Mihai AB - Microbial infections still represent one of the major causes of mortality and morbidity worldwide. Irrational usage of antimicrobials has lead to increased resistance, causing clinical, social and economical disabilities. Therefore, one of the major challenges of scientists is to develop novel alternative methods to handle infections and reduce resistance and other side effects produced by the actual therapies. The aim of this book is to offer a perspective on novel approaches to handle infections by using naturally-derived products in order to modulate the virulence of pathogens, without the risk of developing resistance. We intend to highlight the utility of microbial, vegetal and animal–derived compounds with potential antimicrobial activity by exploiting their effect on microbial virulence. Furthermore, this book aims to reveal the potential to assimilate recent bio-technological findings, like the usage of nanotechnology as efficient shuttles for stabilizing, improved targeting and the controlled release of natural products in order to efficiently fight infections. DO - 10.1515/9783110449501 ID - OAPEN ID: 17962 KW - virulence KW - molecular modulation KW - antimicrobial therapy KW - drug delivery nanoshuttles L1 - https://doi.org/10.1515/9783110449501 LA - English LK - https://directory.doabooks.org/handle/20.500.12854/54879 PB - De Gruyter PY - 2015 SN - 9783110449501 SN - 9783110449617 TI - Novel Molecular Approaches to Target Microbial Virulencenull ER -