TY  - BOOK
AU  - Miklos Fuzi
AU  - Margaret Ip
AB  - Multiresistant bacterial pathogens pose a serious problem worldwide making the appropriate treatment of patients with healthcare-associated infections a challenge. The spread of antibiotic resistance is either mediated by mobile genetic elements (MGEs) or the dissemination of genetically-related groups of pathogens, “high-risk clonal complexes”. Interestingly most multiresistant healthcare-associated bacteria command just a few dominant international clonal complexes causing infections in various geographical areas. It is of utmost importance to identify the determinants associated with and promoting the spread of antibiotic resistance and the dissemination of these multiresistant pathogens. The Topic comprises mostly of population and epidemiological studies investigating antibiotic resistance mechanisms, MGEs and the impact of antibiotic resistance, and the production of virulence factors on the clonal dynamics of a diverse range of bacterial species. Though, the exploration of the mechanisms governing clonal dynamics and the dissemination of antibiotic resistance will remain a salient issue for a considerable time to come we believe that the papers published in the Topic have usefully contributed to the better understanding of some of the processes involved and supplement papers investigating the “non-bacterial” constituents of clonal mobility, like proper medical practice and compliance with hygienic standards.
DO  - 10.3389/978-2-88945-217-0
ID  - OAPEN ID: 24022
KW  - antibiotic resistance
KW  - dissemination
KW  - pathogen
KW  - Clone
L1  - http://journal.frontiersin.org/researchtopic/3724/the-global-challenge-posed-by-the-multiresistant-international-clones-of-bacterial-pathogens
LA  - English
LK  - https://directory.doabooks.org/handle/20.500.12854/48671
PB  - Frontiers Media SA
PY  - 2017
SN  - 9782889452170
TI  - The Global Challenge Posed by the Multiresistant International Clones of Bacterial Pathogensnull
ER  - 
