TY  - BOOK
AU  - Blanco, Juan C.
AU  - Reguera, Beatriz
AB  - Several species of Dinophysis produce one or two groups of lipophilic toxins: okadaic acid (OA) and its derivatives; or the dinophysistoxins (DTXs) (also known as diarrhetic shellfish poisons or DSP toxins) and pectenotoxins (PTXs). DSP toxins are potent inhibitors of protein phosphatases, causing gastrointestinal intoxication in consumers of contaminated seafood. Forty years after the identification of Dinophysis as the causative agent of DSP in Japan, contamination of filter feeding shellfish exposed to Dinophysis blooms is recognized as a problem worldwide. DSP events affect public health and cause considerable losses to the shellfish industry. Costly monitoring programs are implemented in regions with relevant shellfish production to prevent these socioeconomic impacts. Harvest closures are enforced whenever toxin levels exceed regulatory limits (RLs). Dinophysis species are kleptoplastidic dinoflagellates; they feed on ciliates (Mesodinium genus) that have previously acquired plastids from cryptophycean (genera Teleaulax, Plagioselmis, and Geminigera) nanoflagellates. The interactions of Dinophysis with different prey regulate their growth and toxin production. When Dinophysis cells are ingested by shellfish, their toxins are partially biotransformed and bioaccumulated, rendering the shellfish unsuitable for human consumption. DSP toxins may also affect shellfish metabolism. This book covers diverse aspects of the abovementioned topics—from the laboratory culture of Dinophysis and the kinetics of uptake, transformation, and depuration of DSP toxins in shellfish to Dinophysis population dynamics, the monitoring and regulation of DSP toxins, and their impact on the shellfish industry in some of the aquaculture regions that are traditionally most affected, namely, northeastern Japan, western Europe, southern Chile, and New Zealand.
DO  - 10.3390/books978-3-03921-364-1
ID  - OAPEN ID: 42539
KW  - WitOMI analysis
KW  - n/a
KW  - DST accumulation
KW  - mussel
KW  - dinophysistoxins
KW  - depuration
KW  - human health
KW  - pectenotoxins (PTXs)
KW  - cryptophytes
KW  - Mesodinium
KW  - dinophysis
KW  - compartmentalization
KW  - resistance
KW  - Japanese scallop
KW  - surf clam
KW  - HAB monitoring
KW  - toxins
KW  - organic matter
KW  - OMI analysis
KW  - PTXs
KW  - time-series
KW  - Diarrhetic shellfish toxins
KW  - predator-prey preferences
KW  - immunity
KW  - okadaic acid
KW  - physical–biological interactions
KW  - defense
KW  - digestion
KW  - Dinophysis
KW  - harmful algal blooms
KW  - pectenotoxin
KW  - El Niño Southern Oscillation
KW  - lysate
KW  - suspended particulate matter (SPM)
KW  - D. caudata
KW  - mixotrophic cultures
KW  - Mytilus galloprovincialis
KW  - bivalves
KW  - diarrhetic shellfish poisoning
KW  - biotransformation
KW  - Mesodinium cf. rubrum
KW  - RNA-Seq
KW  - DST esterification
KW  - Mesodinium rubrum
KW  - statistical analysis
KW  - seasonality
KW  - mass culture conditions
KW  - D. acuminata-complex
KW  - Argopecten purpuratus
KW  - harmful algal bloom
KW  - pipis (Plebidonax deltoides)
KW  - DTX-2
KW  - Reloncaví Fjord
KW  - pectenotoxins
KW  - deep sequencing
KW  - climatic anomaly
KW  - Brazil
KW  - qPCR
KW  - high throughput sequencing
KW  - DSP
KW  - accumulation
KW  - LC/MS/MS
KW  - Protoceratium reticulatum
KW  - shellfish toxicity
KW  - transcriptomic response
KW  - New Zealand
KW  - blooms
KW  - trophic transfer
KW  - metabolism
KW  - bacterial community
KW  - kinetics
KW  - marine biotoxins
KW  - diarrhetic shellfish toxins
KW  - bivalve shellfish
KW  - Diarrhetic Shellfish Toxins (DST)
KW  - diarrhetic shellfish toxins (DST)
KW  - Scotland
KW  - Dinophysis acuminata
KW  - DSP toxins
KW  - toxin accumulation
KW  - Southern Annual Mode
KW  - Diarrheic Shellfish Poisoning
KW  - Dinophysis toxins
KW  - OA
KW  - marine toxins
KW  - toxin vectors
KW  - wild harvest
KW  - Dinophysis acuta
KW  - Sydney rock oyster (Saccostrea glomerata)
KW  - Argopecten irradians
KW  - dinophysistoxin
KW  - Port Underwood
KW  - aquaculture
KW  - niche partitioning
L1  - https://mdpi.com/books/pdfview/book/1570
LA  - English
LK  - https://directory.doabooks.org/handle/20.500.12854/45199
PB  - MDPI - Multidisciplinary Digital Publishing Institute
PY  - 2019
SN  - 9783039213634
SN  - 9783039213641
TI  - Dinophysis Toxins: Distribution, Fate in Shellfish and Impactsnull
ER  - 
