TY  - BOOK
AU  - Uekusa, Hidehiro
AU  - Yonemochi, Etsuo
AB  - The crystalline state is the most commonly used essential solid active pharmaceutical ingredient (API). The characterization of pharmaceutical crystals encompasses many scientific disciplines, but the core is crystal structure analysis, which reveals the molecular structure of essential pharmaceutical compounds. Crystal structure analysis provides important structural information related to the API's wide range of physicochemical properties, such as solubility, stability, tablet performance, color, and hygroscopicity. This book entitled “Pharmaceutical Crystals"" focuses on the relationship between crystal structure and physicochemical properties. In particular, the new crystal structure of pharmaceutical compounds involving multi-component crystals, such as co-crystals, salts, and hydrates, and polymorph crystals are reported. Such crystal structures were investigated in the latest studies that combined morphology, spectroscopic, theoretical calculation, and thermal analysis with crystallographic study. This book highlights the importance of crystal structure information in many areas of pharmaceutical science and presents current trends in the structure–property study of pharmaceutical crystals. The Guest Editors of this book hope the readers enjoy a wide variety of recent studies on Pharmaceutical Crystals.
DO  - 10.3390/books978-3-03928-713-0
ID  - OAPEN ID: 45988
KW  - crystal structure analysis
KW  - n/a
KW  - famotidine
KW  - solution crystallization
KW  - salt optimization
KW  - structure determination from powder diffraction data
KW  - Hirshfeld surface analysis
KW  - DFT
KW  - molecular docking study
KW  - melting diagram
KW  - dehydration
KW  - hygroscopicity
KW  - HBV
KW  - Benzodioxole
KW  - pharmaceutical crystals
KW  - 4-b]indol-4-one
KW  - pyrimidin-4(3H)-one
KW  - liquid assisted grinding
KW  - HOMO-LUMO
KW  - dissolution
KW  - cocrystal formation
KW  - Raman spectroscopy
KW  - carbamazepine
KW  - hydrogen bonding
KW  - 3
KW  - ondansetron
KW  - physicochemical properties
KW  - solubility
KW  - succinic acid
KW  - cocrystal
KW  - adefovir dipivoxil
KW  - hepatitis B
KW  - polymorphs
KW  - hydrogen-bond-acceptance ability
KW  - DFT study
KW  - Nitrofurantoin–4-dimethylaminopyridine (NF-DMAP) salt
KW  - photostability
KW  - on-line monitoring
KW  - 5-dihydro-4H-pyrimido[5
KW  - Imidazole
KW  - Semicarbazone
KW  - crystal habit
KW  - Crystal structure
KW  - solvent-mediated polymorphic transformation
KW  - ticagrelor
KW  - hydrate
KW  - pharmaceutical cocrystal
KW  - malonic acid
KW  - 1H-indole
KW  - reactivity descriptors
KW  - famoxadone
KW  - crystal structure
KW  - dicarboxylic acid
KW  - hydrogen bond
KW  - saccharin
L1  - https://mdpi.com/books/pdfview/book/2162
LA  - English
LK  - https://directory.doabooks.org/handle/20.500.12854/56130
PB  - MDPI - Multidisciplinary Digital Publishing Institute
PY  - 2020
SN  - 9783039287123
SN  - 9783039287130
TI  - Pharmaceutical Crystalsnull
ER  - 
