TY  - BOOK
AU  - Carlson, Ross
AU  - Sauro, Herbert
AB  - Modern biology is rapidly becoming a study of large sets of data. Understanding these data sets is a major challenge for most life sciences, including the medical, environmental, and bioprocess fields. Computational biology approaches are essential for leveraging this ongoing revolution in omics data. A primary goal of this Special Issue, entitled “Methods in Computational Biology”, is the communication of computational biology methods, which can extract biological design principles from complex data sets, described in enough detail to permit the reproduction of the results. This issue integrates interdisciplinary researchers such as biologists, computer scientists, engineers, and mathematicians to advance biological systems analysis. The Special Issue contains the following sections:•Reviews of Computational Methods•Computational Analysis of Biological Dynamics: From Molecular to Cellular to Tissue/Consortia Levels•The Interface of Biotic and Abiotic Processes•Processing of Large Data Sets for Enhanced Analysis•Parameter Optimization and Measurement
DO  - 10.3390/books978-3-03921-164-7
ID  - OAPEN ID: 35889
KW  - n/a
KW  - inosine
KW  - immune checkpoint inhibitor
KW  - geometric singular perturbation theory
KW  - simulation
KW  - BioModels Database
KW  - ADAR
KW  - calcium current
KW  - bifurcation analysis
KW  - bacterial biofilms
KW  - nonlinear dynamics
KW  - explanatory model
KW  - turning point bifurcation
KW  - oscillator
KW  - workflow
KW  - bioreactor integrated modeling
KW  - modeling methods
KW  - elementary flux modes visualization
KW  - multiscale systems biology
KW  - evolutionary algorithm
KW  - metabolic model
KW  - differential evolution
KW  - reduced-order model
KW  - computational model
KW  - gut microbiota dysbiosis
KW  - canard-induced EADs
KW  - computational biology
KW  - metabolic modelling
KW  - methods
KW  - SREBP-2
KW  - mechanistic model
KW  - systems modeling
KW  - biological networks
KW  - macromolecular composition
KW  - provenance
KW  - flux balance analysis
KW  - immunotherapy
KW  - compartmental modeling
KW  - immuno-oncology
KW  - metabolic network visualization
KW  - mechanism
KW  - bistable switch
KW  - Clostridium difficile infection
KW  - bioreactor operation optimization
KW  - microRNA targeting
KW  - CFD simulation
KW  - biomass reaction
KW  - RNA editing
KW  - ordinary differential equation
KW  - metabolic modeling
KW  - mass-action networks
KW  - hybrid model
KW  - multiple time scales
KW  - quantitative systems pharmacology (QSP)
KW  - mathematical modeling
KW  - microRNA
KW  - cancer
KW  - parameter optimization
KW  - Hopf bifurcation
KW  - breast
L1  - https://mdpi.com/books/pdfview/book/1403
LA  - English
LK  - https://directory.doabooks.org/handle/20.500.12854/53322
PB  - MDPI - Multidisciplinary Digital Publishing Institute
PY  - 2019
SN  - 9783039211630
SN  - 9783039211647
TI  - Methods in Computational Biologynull
ER  - 
