TY  - BOOK
AU  - Jonathan H. Tobias
AB  - This research topic is focused on recent advances in our understanding of effects of mechanical loading on the skeleton, and research methods used in addressing these. Though it is well established that mechanical loading provides an essential stimulus for skeletal growth and maintenance, there have been major advances recently in terms of our understanding of the molecular pathways involved, which are thought to provide novel drug targets for treating osteoporosis. The articles included in this topic encompass the full spectrum of laboratory and clinical research, and range from review articles, editorials, hypothesis papers and original research articles. Together, they demonstrate how mechanical loading underpins many aspects of bone biology, including the pathogenesis and treatment of osteoporosis and other clinical disorders associated with skeletal fragility.
DO  - 10.3389/978-2-88919-751-4
ID  - OAPEN ID: 18871
KW  - mechanical loading
KW  - bone architecture
KW  - accelerometers
KW  - osteoblast
KW  - osteoporosis
KW  - osteoclast
KW  - fractures
KW  - distraction osteogenesis
L1  - http://journal.frontiersin.org/researchtopic/1999/mechanical-loading-and-bone
LA  - English
LK  - https://directory.doabooks.org/handle/20.500.12854/52929
PB  - Frontiers Media SA
PY  - 2016
SN  - 9782889197514
TI  - Mechanical Loading and Bonenull
ER  - 
