TY - BOOK AU - Keglevich, György AB - Organophosphorus chemistry is an important discipline within organic chemistry. Phosphorus compounds, such as phosphines, trialkyl phosphites, phosphine oxides (chalcogenides), phosphonates, phosphinates and >P(O)H species, etc., may be important starting materials or intermediates in syntheses. Let us mention the Wittig reaction and the related transformations, the Arbuzov- and the Pudovik reactions, the Kabachnik–Fields condensation, the Hirao reaction, the Mitsunobu reaction, etc. Other reactions, e.g., homogeneous catalytic transformations or C-C coupling reactions involve P-ligands in transition metal (Pt, Pd, etc.) complex catalysts. The synthesis of chiral organophosphorus compounds means a continuous challenge. Methods have been elaborated for the resolution of tertiary phosphine oxides and for stereoselective organophosphorus transformations. P-heterocyclic compounds, including aromatic and bridged derivatives, P-functionalized macrocycles, dendrimers and low coordinated P-fragments, are also of interest. An important segment of organophosphorus chemistry is the pool of biologically-active compounds that are searched and used as drugs, or as plant-protecting agents. The natural analogue of P-compounds may also be mentioned. Many new phosphine oxides, phosphinates, phosphonates and phosphoric esters have been described, which may find application on a broad scale. Phase transfer catalysis, ionic liquids and detergents also have connections to phosphorus chemistry. Green chemical aspects of organophosphorus chemistry (e.g., microwave-assisted syntheses, solvent-free accomplishments, optimizations, and atom-efficient syntheses) represent a dynamically developing field. Last, but not least, theoretical approaches and computational chemistry are also a strong sub-discipline within organophosphorus chemistry. DO - 10.3390/books978-3-03928-237-1 ID - OAPEN ID: 44773 KW - synergy KW - 1-(acylamino)alkylphosphonic acids KW - hydrolytic deacylation KW - chiral phosphines KW - organophosphorus chemistry KW - alcoholysis KW - electrophilic substitution KW - NORPHOS KW - DFT KW - diphosphines KW - dry eye syndrome KW - cyclo-P5 KW - O-derivatization KW - triple-decker KW - phosphorylation KW - molybdenum KW - NMR-controlled titration KW - mechanochemistry KW - N-acyliminium cation KW - stability constants KW - Pudovik reaction KW - phosphonocarboxylic acids KW - 1 KW - aminophosphonic acids KW - allylic alkylation KW - diquafosol KW - silver KW - Diels-Alder reaction KW - QTAIM KW - dissociation constants KW - weakly coordinating KW - substitution KW - phosphonium salts KW - amino acids KW - continuous flow reactor KW - DFT calculations KW - metallacycle KW - 31P NMR spectra of intermediates KW - dinucleotides KW - N-acylimine KW - copper KW - microwave KW - 1-aminoalkylphosphonic acids KW - phosphonic acids KW - bis(phosphane) palladium complex KW - denufosol KW - oxidation KW - C-H bond activation KW - asymmetric catalysis KW - dynamic and specific NMR parameters KW - electronic parameters KW - dialkyl H-phosphonates KW - ?-hydroxyphosphonate KW - transesterification KW - polycyclic compounds KW - stereoselective synthesis KW - rearrangement KW - hydrolysis KW - ?-amidoalkylating agents KW - 3-azaphospholes L1 - https://mdpi.com/books/pdfview/book/2050 LA - English LK - https://directory.doabooks.org/handle/20.500.12854/55412 PB - MDPI - Multidisciplinary Digital Publishing Institute PY - 2020 SN - 9783039282364 SN - 9783039282371 TI - Organophosphorus Chemistry 2018null ER -