TY - BOOK AU - Marcelo Tolmasky AU - Jun Lin AU - Marilyn C. Roberts AU - Kunihiko Nishino AU - Lixin Zhang AU - Rustam I. Aminov AB - Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens. DO - 10.3389/978-2-88919-526-8 ID - OAPEN ID: 17822 KW - Metagenomics KW - Antibiotic resistance mechanisms KW - combination therapy KW - antibiotics KW - antibiotic resistance reservoirs L1 - http://journal.frontiersin.org/researchtopic/942/mechanisms-of-antibiotic-resistance LA - English LK - https://directory.doabooks.org/handle/20.500.12854/52943 PB - Frontiers Media SA PY - 2015 SN - 9782889195268 TI - Mechanisms of antibiotic resistancenull ER -