TY  - BOOK
AU  - Miroslav Blumenberg
AB  - Keratin is the proteinaceous body covering layer produced by mammals, birds, fish, reptiles, and amphibians. Hair and wool, horns, claws, hooves, feathers, and scales are made of keratin. Keratin is insoluble in water and is resistant to proteolysis. Importantly, keratin is also the intracellular structural protein that protects living epithelial cells from mechanical damage or stress. The fundamental keratin functions are revealed in congenital human skin diseases caused by mutations in keratin genes, e.g., Epidermolysis bullosa simplex or Epidermolytic hyperkeratosis. Most keratin gene mutations have a dominant-negative effect disrupting the filamentous structure formation even from the natural allele, and leaving the cell with a deficient cytoskeleton. However, industrial scale meat production results in vast quantities of keratin byproduct. Processing this byproduct is, on the one hand a major challenge, and on the other hand, a potential for useful recycling and exploitation.
DO  - 10.5772/intechopen.73230
ID  - OAPEN ID: 37673
KW  - Life Sciences
KW  - Genetics and Molecular Biology
KW  - Biochemistry
KW  - Cell Biology
L1  - https://www.intechopen.com/books/keratin
LA  - English
LK  - https://directory.doabooks.org/handle/20.500.12854/51075
PB  - IntechOpen
PY  - 2018
SN  - 9781789848052
SN  - 9781789848045
TI  - Keratinnull
ER  - 
